Biochemistry

Organic solvents were used to either precipitate enzyme or to study denaturation. The reason why nonaqueous enzymology has generated so much excitement is that enzymes exhibit striking new properties in organic solvents. For example, in organic solvents enzymes often catalyze reactions impossible in water and are very stable. Furthermore, enzyme selectivity in organic solvents is […]

In the Golgi-ER retrograde pathway, sorting of membrane proteins occurs throughout the interaction of coat proteins with their cytoplasmic domains. A putative dilysine motif is present within the C-terminal domain (-6 to -7) of the KDEL receptor. This dilysine motif is required for interaction with coatomer (COPI is a coatomer, a protein complex that coats vesicles